GHUCCTS

News

Share This
  • May 05, 2021

Mayo Clinic Site Feasibility Questionnaire: A Multicenter Study of Detection of Low Ventricular Ejection Fraction (LVEF)

Mayo Clinic is seeking collaborators to participate in a retrospective validation study of an ECG-based artificial intelligence algorithm for the detection of low left ventricular ejection fraction (LVEF) that we have previously developed[i]. The validation results will be submitted to the FDA as part of a De Novo software as a medical device (SAMD) application. This study is fully funded by Mayo Clinic and an opportunity to develop a long-term academic collaboration for future validation studies and publications.

Investigators from participating sites will have full authorship in all resulting research publications from this external validation study.

Site Requirements:

  • Ability to access and send 12-lead ECG data in raw digital format (.csv or .xml files).
  • Provide 3000+ ECGs from patients who have one or more risk factors for heart failure with a corresponding echocardiogram within 14 days of the ECG
  • Ability to automate extraction of demographic information and clinical risk factors for heart failure from the EMR
  • The LVEF must be estimated using the Simpson biplane method and a process should be in place to exclude any LVEF estimations calculated via a different method
  • Ability to complete the agreement, IRB approval and study execution in a short timeframe

If you have an interest in participating or would like to learn more, please contact RSTCVINN@mayo.edu.

Download Questionnaire

[1] Attia ZI, Kapa S, Lopez-Jimenez F, McKie PM, Ladewig DJ, Satam G, Pellikka PA, Enriquez-Sarano M, Noseworthy PA, Munger TM, Asirvatham SJ, Scott CG, Carter RE, Friedman PA. Screening for cardiac contractile dysfunction using an artificial intelligence-enabled electrocardiogram. Nat Med. 2019 Jan;25(1):70-74. doi: 10.1038/s41591-018-0240-2. Epub 2019 Jan 7. PMID: 30617318.

Related News

Funding Opportunity: GHUCCTS 2023-2024 Pilot Awards

Feb 16, 2023

GHUCCTS is pleased to announce the launch of our 2023-2024 GHUCCTS Pilot Awards application cycle. Applicants must have a full-time faculty appointment at one of the GHUCCTS institutions (Howard, Georgetown, DCVA, Medstar, ORNL). Each application should identify a Contact PI who will be responsible for coordinating and submitting the application. Applications are due Monday, March 20, 2023.

GHUCCTS announces 2022 KL2 Scholar Dr. Amanda Blair Spence

Nov 07, 2022

The Georgetown-Howard Universities Center for Clinical and Translational Science (GHUCCTS) is pleased to announce the appointment of Amanda Blair Spence, MD as the 2nd KL2 Scholar selected in our highly-competitive 2022 cycle. This new awardee, her research projects, and training plan are emblematic of our program objectives in that they pair a highly-promising junior faculty scholar-trainee with a mentor team that includes senior colleagues from across disciplines, departments, campuses, and institutions to pursue research that depends upon collaborations and methods from outside the scholars’ discipline, local research environment, or past experiences.

2022 DC CTSA Conference Recordings

Nov 01, 2022

Session recordings are now available from the DC CTSA Consortium's 2022 DC CTSA Spring Regulatory Update & Hot Topics in Clinical and Translational Research.

Close